Getting started with Repatha®

What is Repatha®?

Repatha® is a medicine used to lower levels of cholesterol.

Why have I been prescribed Repatha®?

Repatha® is used along with diet and in combination with usual therapy, including cholesterol-lowering medications called statins, to reduce the risk of heart attack, stroke, and certain heart procedures (to restore blood flow to the heart) in adult patients who have cardiovascular disease.

Repatha® is also used alone or together with other cholesterol-lowering medicines, along with diet, in adults with primary hyperlipidemia (high cholesterol level in your blood) to reduce LDL cholesterol.

Repatha® is also used along with diet and other LDL lowering therapies in people with homozygous familial hypercholesterolemia 12 years and older (an inherited condition that causes high levels of LDL), who need additional lowering of LDL cholesterol.

You should stay on your cholesterol-lowering diet while taking this medicine.

How does Repatha® lower cholesterol?

Evolocumab, the active ingredient of Repatha®, works by helping the liver’s ability to remove LDL-C, or “bad” cholesterol, from the blood. Evolocumab also lowers the level of the fatty substances called triglycerides, and raises the level of HDL-C, often referred to as “good” cholesterol.

Does Repatha® cause any side effects?

Possible side effects include:

  • Flu or flu-like symptoms (high temperature, sore throat, runny nose, cough and chills)
  • Common cold, such as runny nose, sore throat or sinus infections (nasopharyngitis or upper respiratory tract infections)
  • Nausea
  • Back pain
  • Joint pain (also known as arthralgia)
  • High blood sugar levels (diabetes)
  • Injection site reactions (redness, bruising, pain, swelling or bleeding)
  • Allergic reactions including rash, hives, red itchy bumps on your skin (urticaria) and in rare cases, swelling of face, mouth, tongue or throat (angioedema)

If you experience any side effects not listed here, or if any side effect becomes bad enough to interfere with your daily activities, contact your healthcare professional.

Patient Support Program

  • Assistance accessing drug coverage
  • One-on-one Repatha® injection training with a nurse
  • Ongoing educational resources on Repatha® and cardiovascular health
  • Nurse support, ongoing personalized contact and treatment reminders