Repatha® safety information

Repatha® is used along with diet and in combination with usual therapy, including cholesterol-lowering medications called statins, to reduce the risk of heart attack, stroke, and certain heart procedures (to restore blood flow to the heart) in adult patients who have cardiovascular disease.

Repatha® is also used alone or together with other cholesterol-lowering medicines, along with diet, in adults with primary hyperlipidemia (high cholesterol level in your blood) to reduce LDL cholesterol.

Repatha® is also used along with diet and other LDL lowering therapies in people with homozygous familial hypercholesterolemia 12 years and older (an inherited condition that causes high levels of LDL), who need additional lowering of LDL cholesterol.

You should stay on your cholesterol-lowering diet while taking this medicine.

Do not use Repatha® if you have ever had an allergic reaction to Repatha® or any of the ingredients in Repatha®.

Do not use Repatha® if you are allergic or sensitive to rubber or latex, as the needle cap on the SureClick Autoinjector contains dry natural rubber. There is no dry natural rubber in the automated mini-doser with prefilled cartridge.

To help avoid side effects and ensure proper use, talk to your healthcare professional before you take Repatha®. Talk about any health conditions or problems you may have.

If you use Repatha® together with a statin and other cholesterol-lowering medicines, please read the package leaflet of that medicine.


Children and adolescents
The use of Repatha® has not been studied in children under 18 years of age being treated for primary hyperlipidemia. The use of Repatha® has not been studied in children under 12 years of age being treated for homozygous familial hypercholesterolemia.

Other medicines and Repatha®
Tell your doctor or pharmacist about all the medications you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

Pregnancy and breastfeeding
Repatha® has not been tested in pregnant women. It is not known if Repatha® will harm your unborn baby.

  • If you are trying to get pregnant or think you may be pregnant when taking Repatha®, inform your doctor.
  • If you are also taking a statin along with Repatha®, stop taking Repatha® and read the package leaflet of the statin that you are taking.

It is not known whether Repatha® is found in breast milk. It is important to tell your doctor if you are breastfeeding or plan to do so. Your doctor will then help you decide whether to stop breastfeeding, or whether to stop taking Repatha®, considering the benefit of breastfeeding to the baby and the benefit of Repatha® to the mother.

If you become pregnant while taking Repatha®, talk to your healthcare provider about registering in the pregnancy exposure registry for Repatha®.

Tell your healthcare professional about all the medications you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines.

Patient Support Program

  • Assistance accessing drug coverage
  • One-on-one Repatha® injection training with a nurse
  • Ongoing educational resources on Repatha® and cardiovascular health
  • Nurse support, ongoing personalized contact and treatment reminders