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Getting started with Repatha

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  • What is Repatha?
    Repatha is a medicine used to lower levels of cholesterol.
  • Why have I been prescribed Repatha?

    Repatha is used:

    • along with diet and in combination with usual therapy, including cholesterol-lowering medications called statins, to reduce the risk of heart attack, stroke, and certain heart procedures (to restore blood flow to the heart) in adult patients who have cardiovascular disease by further lowering low-density lipoprotein (LDL) cholesterol.
    • along with diet, alone or together with other cholesterol-lowering therapies, in adults with primary hyperlipidemia (high LDL cholesterol level in your blood) to reduce LDL cholesterol.
    • along with diet and other cholesterol-lowering therapies, to reduce LDL cholesterol in people 10 years and older who need additional lowering of the high LDL cholesterol in their blood because of a condition that runs in their family (heterozygous familial hypercholesterolemia [HeFH]).
    • along with diet and other cholesterol-lowering therapies, to reduce LDL cholesterol in people 10 years and older who need additional lowering of the high LDL cholesterol in their blood because of a condition that runs in their family (homozygous familial hypercholesterolemia [HoFH]).

    You should stay on your cholesterol-lowering diet while taking this medicine.

  • How does Repatha lower cholesterol?

    Evolocumab, the active ingredient in Repatha, works by helping the liver’s ability to remove LDL-C, or “bad” cholesterol, from the blood. Evolocumab also lowers the level of the fatty substances called triglycerides, and raises the level of HDL-C, often referred to as “good” cholesterol.

  • Does Repatha cause any side effects?

    Like all medicines, Repatha can cause side effects, although not everybody gets them. The following are not all the possible side effects you may have when taking Repatha.

    • Flu or flu-like symptoms (high temperature, sore throat, runny nose, cough, and chills)
    • Common cold, such as runny nose, sore throat, or sinus infections (nasopharyngitis or upper respiratory tract infections)
    • Nausea
    • Back pain
    • Joint pain (arthralgia)
    • Muscle pain (myalgia), with or without associated muscle weakness
    • Injection site reactions (redness, bruising, pain, swelling, or bleeding)
    • Allergic reactions, including severe rash, rash, hives, red itchy bumps on your skin (urticaria), and, in rare cases, swelling of face, mouth, tongue, or throat (angioedema), redness, severe itching, swollen face, or trouble breathing

If you have a troublesome symptom or side effect that is not listed here or becomes bad enough to interfere with your daily activities, tell your healthcare professional.

HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol

Patient Support Program

Do you have questions?

Connect with the Amgen Canada Medical Information team for help by phone at 1-866-502-6436 or email at medinfocanada@amgen.com.

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