WOMAN EXAMINES AUTOINJECTOR WOMAN EXAMINES AUTOINJECTOR

How to use the SureClick autoinjector

Here are the main steps of using the SureClick autoinjector.

Once you have been trained to administer Repatha, please refer to the Patient Medication Information leaflet that comes with your Repatha medication for step-by-step instructions and helpful illustrations.

Ask your doctor if you have any further questions on how to use Repatha.

  • Step 1: Preparing to inject Repatha
    WOMAN LOOKING AT CARTON SHE TOOK FROM THE FRIDGEWOMAN LOOKING AT CARTON SHE TOOK FROM THE FRIDGE
    • Remove one SureClick autoinjector from the carton. Wait at least 30 minutes for the autoinjector to reach room temperature before injecting.
      • Do not try to warm the autoinjector by using a heat source such as hot water or a microwave.
      • Do not leave the autoinjector in direct sunlight.
      • Do not shake the autoinjector.
      • Do not remove the orange cap from the autoinjector yet.
    • Inspect the SureClick autoinjector to make sure the medicine in the window is clear and colourless to slightly yellow.
      • Do not use the autoinjector if: the medicine is cloudy or discoloured or contains large lumps, flakes, or particles; any part appears cracked or broken; the autoinjector has been dropped; the orange cap is missing or not securely attached; the expiration date printed on the label has passed.
    • Wash your hands thoroughly with soap and water and gather all materials needed for your injection on a clean, well-lit surface: alcohol wipes; cotton ball or gauze pad; adhesive bandage; sharps disposal container.
    • Prepare and clean your injection site with an alcohol wipe. Only use these injection sites: thigh; stomach (abdomen), except for a 5-centimetre (2-inch) area around your navel (belly button); outer area of upper arm (only if someone else is giving the injection). Do not touch this area again before injecting.
    • Choose a different site each time you give yourself an injection. If you want to use the same injection site, make sure it is not the same spot you used for the last injection. Do not inject into areas where skin is tender, bruised, red, or hard. Avoid injecting into areas with scars or stretch marks, or into raised, thick, red, or scaly skin patches or lesions.
  • Step 2: Get ready
    WOMAN IS SWABBING HIMSELFWOMAN IS SWABBING HIMSELF

    Pull the orange cap straight off only when you are ready to inject.

    • Do not leave the orange cap off for more than 5 minutes. This can dry out the medicine and may clog the needle when you take the injection.

      • It is normal to see a drop of liquid at the end of the needle or yellow safety guard.
      • Do not twist, bend, or wiggle the orange cap.
      • Do not put the orange cap back onto the autoinjector.
      • Do not put fingers into the yellow safety guard.
      • Do not remove the orange cap from the autoinjector until you are ready to inject.
      If you are unable to inject, please contact your healthcare provider.
    • Create a firm surface at the selected injection site (thigh, stomach, or outer areas of the upper arm), by using either the Stretch method or the Pinch method.
      • Stretch the skin firmly by moving your thumb and fingers in opposite directions, creating an area about 5-centimetres (2-inches) wide.

        OR
      • Pinch the skin firmly between your thumb and fingers, creating an area about 5-centimetres (2-inches) wide.
    • It is important to keep skin stretched or pinched while injecting.
  • Step 3: Inject
    WOMAN IS INJECTING HERSELFWOMAN IS INJECTING HERSELF
    • Keep holding the stretched or pinched skin. With the orange cap off, put the yellow safety guard on your skin at a 90-degree angle. The needle is inside the yellow safety guard. Do not touch the grey start button yet.
    • Firmly push the autoinjector down onto your skin until it stops moving. It is important that you push the autoinjector all the way down onto the injection site but do not touch the grey start button until you are ready to inject.
    • When you are ready to start the injection, press the grey start button. You will hear a CLICK.
    • Keep pushing the autoinjector down on the skin. Then lift your thumb while still holding the autoinjector on your skin. The injection may take up to 15 seconds to complete.
    • The window turns from clear to yellow when the injection is done. You may hear a second CLICK.
    • NOTE: After you remove the autoinjector from your skin, the needle will be automatically covered.

    Important: When you remove the autoinjector, if the window has not turned yellow, or if it looks like the medicine is still injecting, this means you have not received a full dose. Call your healthcare provider immediately.

    What will happen if I press the grey start button before I am ready to do the injection on my skin?
    The injection will only happen when the grey start button is pressed and the autoinjector is pushed onto the injection site. Release the grey start button and push the autoinjector down until the yellow safety guard stops moving. Then, you can push the grey start button again.

    Can I release the grey start button after I start my injection?
    You can release the grey start button, but continue to hold the autoinjector firmly against your skin during the injection.

    Will the grey start button pop up after I release my thumb?
    The grey start button may not pop up after you release your thumb if you held your thumb down during the injection. This is okay.

    What do I do if I did not hear a second click?
    If you did not hear a second click, you can confirm a complete injection by checking that the window has turned yellow.

  • Step 4: Finish
    WOMAN PUTS AUTOINJECTOR IN SHARPS CONTAINERWOMAN PUTS AUTOINJECTOR IN SHARPS CONTAINER

    Throw away (dispose of) the used autoinjector and orange needle cap in a sharps disposal container right away after use.

    • Do not throw away the autoinjector and orange needle cap in your household trash unless your community guidelines permit this. Do not recycle your used sharps disposal container.
    • Do not reuse the autoinjector, do not recap the autoinjector, and do not put fingers into the yellow safety guard.
    • If you do not have a sharps disposal container, you may use a household container that is:
      • made of a heavy-duty plastic,
      • closed with a tight-fitting, puncture-resistant lid that does not allow sharps to come out,
      • upright and stable during use,
      • leak-resistant, and
      • properly labelled to warn of hazardous waste inside the container.
    • Examine the injection site. If there is blood, press (do not rub) a cotton ball or gauze pad on the injection site. Apply a bandage if needed.

Patient Support Program

Do you have questions?

Connect with the Amgen Canada Medical Information team for help by phone at 1-866-502-6436 or email at medinfocanada@amgen.com.